Gastro Education

Andreas Hillenbrand graduated from Medical Center of the University of Munich - LMU Munich in 2000 and started his surgical career in Ulm. After completing his specialist examination in surgery in 2008, he was focused on general and endocrine surgery.

Non-alcoholic fatty liver disease (NAFLD), defined by non-alcohol related excessive fat accumulation in the liver, is a leading cause of chronic liver disease worldwide. Obesity is a major risk factor for NAFLD. Although simple steatosis carries a relatively benign prognosis, a significant proportion of patients will progress to non-alcoholic steatohepatitis (NASH). NASH is the advanced form of NAFLD, leading to liver cirrhosis, end-stage liver disease, and hepatocellular carcinoma. In this retrospective study, we analyzed 136 liver samples obtained from patients operated upon in our surgical department and determined the prevalence of NASH in relation to gender and body mass index (BMI). Furthermore, we assessed the association of NASH with the length of the small bowel measured intraoperatively. Simple steatosis of the liver is highly prevalent especially in the obese. In our study, we found steatosis of the liver in more than 80% of morbidly obese patients, however, probable/definite NASH was found in only 30% of these patients (and a further 30% of these patients were classified as uncertain NASH). The exact pathogenesis and natural history are still being defined. Therapy currently addresses the features of metabolic syndrome, including diabetes, obesity, and dyslipidemia, however, if a connection between NASH and small bowel length is confirmed, malabsorptive bariatric surgery should be considered as a further option.

Mofeed M Selim has completed his PhD from Mansoura University (January 2018). He is currently a Consultant of Medical Laboratory at the National Cancer Institute of Cairo University. He has published 3 papers in reputed journals.

Introduction: Hepatitis C is an infectious disease that affects the liver. Its complication is a major high risk groups that may be lead to hepatocellular carcinoma HCC, so natural prevention is required. The combination of magic fruit and honey bee was used in the treatment of HCV patients were treated with 4 gm from Magic fruit and 1 gm from Honey bee 3 times daily for three months. Patients & Methods: Our group study was conducted on 50 patients with chronic hepatitis C (the male number was 35 while the female was 15; the median age was 45 years) was taken from the outpatient clinics of National Cancer Institute, Egypt. Results: The mean values of virus C level, which was determined by real time PCR and FoxP3 protein which was measured by ELISA in sera of patients with chronic hepatitis infection (CHI), showed highly significant decrease after treatment. Hence the results have shown improvements in liver function, kidney function, and CBC tests for the HCV patients post-treatment. Moreover the results also revealed that, highly significant decreased of CD4 + CD25 expression by flow cytometric analysis was observed in the mononuclear leukocytes isolated from the patients after treatment. Conclusions: A combination of magic fruit and honey bee could be useful protective natural agents against human hepatocarcinogenesis induced by HCV infection. Further study is strongly recommended for large populations and prolonged treatment for 9-12 months.